The human placenta is a rich source of various growth factors and cytokines such as Epidermal Growth Factor (EGF), Transforming Growth Factor-beta (TGF-β), Fibroblast Growth Factor (FGF), Platelet-Derived Growth Factor (PDGF), and Vascular Endothelial Growth Factor (VEGF). The placenta is also composed of collagen types I, III, IV, V, and VI, fibronectin, laminin, vitronectin, elastin, and proteoglycans. Due to its embryonic origin, it can possess unique flexibility and differentiation capabilities. The placenta, which is usually discarded after birth, is a rich source of extracellular matrix (ECM) and can be an alternative source for producing three-dimensional scaffolds aimed at creating small grafts. One of the advantages of using placental tissue is that it does not require an invasive method to obtain the necessary tissue for research and wound dressing production.
History:
The amniotic membrane has the longest history of use in modern medicine among all placental tissues. In **1910**, the amniotic membrane was first used in skin grafting, and then in **1913**, it was first utilized in the treatment of skin wounds. Today, this membrane is extensively studied for its use in wound healing, easily transforming into a wound dressing.
Studies Conducted:
Multiple studies have been conducted by this company's Research and Development group on the use of decellularized placental tissue for tissue engineering applications. In one of these studies, the anti-inflammatory and bacteria-eliminating properties of placental tissue were investigated by adding short antimicrobial peptides. The results of numerous studies conducted by this company's Research and Development group showed that the placenta can be used as a scaffold, wound dressing, and for skin wound repair.
Outlook for Placenta Use:
Today, fetal placental extract has been proven to stimulate cell regeneration, reduce inflammation, and treat various tissue and cellular lesions and improve wound healing. For this reason, the use of placental extract has gained attention as an effective treatment method in regenerative medicine and is capable of treating certain diseases. This company's Research and Development group is continuously developing and optimizing these products. By continuing research and participating in clinical trials, we hope to expand the scope of use for these products and contribute to improving patient health at both national and international levels.
If you would like to learn more about our products and research, please contact us or visit the research section of our website. With your support, we are taking an effective step towards advancing science and new treatments.